Achieving a cure for hypothalamic hamartomas: a Sisyphean quest?
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چکیده
منابع مشابه
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متن کاملHypothalamic Hamartomas: Two Cases
This is a MRI study of two patients presented with history of gelastic seizures since many years ago. Plain and post intravenous gadolinium multiplanar MRI imaging of the brain is performed. It showed well-defined non-enhancing mass lesions in the region of hypothalamus and tuber cinereum. It showed signal intensity similar to the gray matter and imaging diagnosis of hypothalamic hamartoma is m...
متن کاملEndoscopic Treatment of Hypothalamic Hamartomas
Hypothalamic hamartoma (HH) is a benign indolent lesion despite the presentation of refractory epilepsy. Behavioral disturbances and endocrine problems are additional critical symptoms that arise along with HHs. Due to its nature of generating epileptiform discharge and spreading to cortical region, various management strategies have been proposed and combined. Surgical approaches with open cra...
متن کاملGelastic epilepsy: Beyond hypothalamic hamartomas
Gelastic epilepsy or laughing seizures have been historically related to children with hypothalamic hamartomas. We report three adult patients who had gelastic epilepsy, defined as the presence of seizures with a prominent laugh component, including brain imaging, surface/invasive electroencephalography, positron emission tomography, and medical/surgical outcomes. None of the patients had hamar...
متن کاملStereotactic surgical approach to hypothalamic hamartomas.
Hypothalamic hamartomas are often associated to a progressive epileptic encephalopathy. Non-invasive data indicates that destruction or isolation of the hamartoma may stop seizures. We present data on patients who underwent stereotactic radiofrequency with or without endoscopy. Epilepsy improved in 60% of patients with minimal morbidity. This approach was less successful in large lesions. These...
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ژورنال
عنوان ژورنال: Epilepsia
سال: 2017
ISSN: 0013-9580
DOI: 10.1111/epi.13773